Cillian Murphyas J. Robert Oppenheimer
Emily Bluntas Kitty Oppenheimer
Matt Damonas Leslie Groves
Robert Downey Jr.as Lewis Strauss
Florence Pughas Jean Tatlock
Josh Hartnettas Ernest Lawrence
Casey Affleckas Boris Pash
Rami Malekas David Hill
Kenneth Branaghas Niels Bohr
